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CFD Antibody

CFD Antibody

Item no.	OACA07383
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections."Sprong T., Roos D., Weemaes C., Neeleman C., Geesing C.L., Mollnes T.E., van Deuren M.Blood 107:4865-4870(2006). [2]"Crystal structure of a complement factor D mutant expressing enhanced catalytic activity."Kim S., Narayana S.V., Volanakis J.E.J. Biol. Chem. 270:24399-24405(1995). [3]"Structure of human factor D. A complement system protein at 2.0-A resolution."Narayana S.V.L., Carson M., El-Kabbani O., Kilpatrick J.M., Moore D., Chen X., Bugg C.E., Volanakis J.E., Delucas L.J.J. Mol. Biol. 235:695-708(1994).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADIPSIN;ADN;C3 convertase activator;complement factor D;complement factor D preproprotein;D component of complement (adipsin);DF;PFD;properdin factor D.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CFD
Gene Fullname	complement factor D
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Nucleotide accession_num	NM_001317335
Protein accession_num	NP_001304264
Protein name	Complement factor D
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Complement factor D protein (26-253AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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