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TRIM23 Antibody

TRIM23 Antibody

Item no.	OACA08893
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Cell Biology Cell Status Adenocarcinoma Cytoskeleton Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining small GTPases Arf Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADP-ribosylation factor domain protein 1,64kDa;ADP-ribosylation factor domain-containing protein 1;ARD1;ARF domain protein 1;ARFD1;E3 ubiquitin-protein ligase TRIM23;GTP-binding protein ARD-1;RING finger protein 46;RING-type E3 ubiquitin transferase TRIM23;RNF46;tripartite motif protein TRIM23;tripartite motif-containing protein 23.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	TRIM23
Gene Fullname	tripartite motif containing 23
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Acts as an E3 ubiquitin-protein ligase. Plays an essential role in autophagy activation during viral infection. Mechanistically, activates TANK-binding kinase 1/TBK1 by facilitating its dimerization and ability to phosphorylate the selective autophagy receptor SQSTM1. In order to achieve this function, TRIM23 mediates 'Lys-27'-linked auto-ubiquitination of its ADP-ribosylation factor (ARF) domain to induce its GTPase activity and its recruitment to autophagosomes (PubMed:28871090).
Nucleotide accession_num	NM_001656
Protein accession_num	NP_001647
Protein name	E3 ubiquitin-protein ligase TRIM23
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human E3 ubiquitin-protein ligase TRIM23 protein (1-280AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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