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BUB1B Antibody

BUB1B Antibody

Item no.	OACA09344
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Cell Biology Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Motor proteins Primary Antibodies By Organ Colorectal Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bub1A;BUB1B,mitotic checkpoint serine/threonine kinase;BUB1beta;BUBR1;budding uninhibited by benzimidazoles 1 homolog beta;hBUBR1;MAD3/BUB1-related protein kinase;MAD3L;mitotic checkpoint kinase MAD3L;mitotic checkpoint serine/threonine-protein kinase BUB1 beta;MVA1;Protein SSK1;SSK1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BUB1B
Gene Fullname	BUB1 mitotic checkpoint serine/threonine kinase B
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.
Nucleotide accession_num	NM_001211
Protein accession_num	NP_001202
Protein name	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein (230-394AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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