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E2F1 Antibody

E2F1 Antibody

Item no.	OACA09364
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Breast Cancer Immunostaining Bone Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E2F-1;PBR3;PRB-binding protein E2F-1;RBAP1;RBAP-1;RBBP3;RBBP-3;RBP3;retinoblastoma-associated protein 1;retinoblastoma-binding protein 3;transcription factor E2F1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	E2F1
Gene Fullname	E2F transcription factor 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Positively regulates transcription of RRP1B (PubMed:20040599).
Nucleotide accession_num	NM_005225
Protein accession_num	NP_005216
Protein name	Transcription factor E2F1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Transcription factor E2F1 protein (133-362AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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