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PMAIP1 Antibody

PMAIP1 Antibody

Item no.	OACA09447
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies Astrocytoma By Organ Breast Cancer Heart & Blood Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adult T cell leukemia-derived PMA-responsive;APR;immediate-early-response protein APR;NOXA;phorbol-12-myristate-13-acetate-induced protein 1;PMA-induced protein 1;protein Noxa.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PMAIP1
Gene Fullname	phorbol-12-myristate-13-acetate-induced protein 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Nucleotide accession_num	NM_021127
Protein accession_num	NP_066950
Protein name	Phorbol-12-myristate-13-acetate-induced protein 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OACA09447-datasheet.pdf

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Amount: 50 ug

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Delivery expected until 12/25/2025

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