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RUNX1T1 Antibody

RUNX1T1 Antibody

Item no.	OACA09570
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Testicular & Prostate Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	acute myelogenous leukemia 1 translocation 1,cyclin-D related;AML1-MTG8;AML1T1;CBFA2T1;CDR;core-binding factor,runt domain,alpha subunit 2; translocated to,1; cyclin D-related;Cyclin-D-related protein;eight twenty one protein;ETO;MTG8;myeloid translocation gene on 8q22;protein CBFA2T1;Protein ETO;Protein MTG8;runt related transcription factor 1; translocated to,1 (cyclin D related);RUNX1 translocation partner 1;zinc finger MYND domain-containing protein 2;ZMYND2.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	RUNX1T1
Gene Fullname	RUNX1 partner transcriptional co-repressor 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588).
Nucleotide accession_num	NM_001198625
Protein accession_num	NP_001185554
Protein name	Protein CBFA2T1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Protein CBFA2T1 protein (416-525AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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