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PAK3 Antibody

PAK3 Antibody

Item no.	OACA10026
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adriamycin resistance-associated;ARA;beta-PAK;bPAK;MRX30;MRX47;oligophrenin-3;OPHN3;p21 (CDKN1A)-activated kinase 3;p21 protein (Cdc42/Rac)-activated kinase 3;p21-activated kinase 3;PAK-3;PAK3beta;serine/threonine-protein kinase PAK 3;XLID30.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PAK3
Gene Fullname	p21 (RAC1) activated kinase 3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Nucleotide accession_num	NM_001128166
Protein accession_num	NP_001121638
Protein name	Serine/threonine-protein kinase PAK 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OACA10026-datasheet.pdf

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Amount: 50 ug

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Delivery expected until 12/25/2025

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