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BCL2 Antibody

BCL2 Antibody

Item no.	OACA10460
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Immunostaining Lymphatic System Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1,regulatory subunit 50.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BCL2
Gene Fullname	BCL2 apoptosis regulator
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Nucleotide accession_num	NM_000633
Protein accession_num	NP_000624
Protein name	Apoptosis regulator Bcl-2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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