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FGG Antibody

FGG Antibody

Item no.	OACD00359
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Neuroscience Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Clone	5#
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	fibrinogen gamma chain;fibrinogen,gamma polypeptide;testicular tissue protein Li 70.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Western blotting: 0.5-5 ug/mL Immunocytochemistry in formalin fixed cells: 5-30 ug/mL Immunohistochemistry in formalin fixed frozen section: 5-30 ug/mL Immunohistochemistry in paraffin section: 5-30 ug/mL Enzyme-linked Immunosorbent Assay: 0.05-2 ug/mL Optimal working dilutions must be determined by end user.
Gene symbol	FGG
Gene Fullname	fibrinogen gamma chain
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Nucleotide accession_num	NM_000509.5
Protein accession_num	NP_000500.2
Protein name	Fibrinogen gamma chain
Clonality	Monoclonal
Purification	Protein A/G Purified
Immunogen	FGG Recombinant Protein (OPCD03223)
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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