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ABCA4 Antibody

ABCA4 Antibody

Item no.	OACD01318
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunocytochemistry Lipid & Fatty Acid Transport Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter,retinal-specific;ATP-binding cassette,sub-family A (ABC1),member 4;ATP-binding transporter,retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunohistochemistry\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	256 kDa
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL
Gene symbol	ABCA4
Gene Fullname	ATP binding cassette subfamily A member 4
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
Nucleotide accession_num	NM_000350
Protein accession_num	NP_000341.2
Protein name	Retinal-specific ATP-binding cassette transporter
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant ABCA4 (Gly1398~Asn1727) expressed in E.coli
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against ABCA4. It has been selected for its ability to recognize ABCA4 in immunohistochemical staining and western blotting.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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