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EPAS1 Antibody (OACD04187)

EPAS1 Antibody (OACD04187)

Item no.	OACD04187
Manufacturer	AVIVA Systems Biology
Amount	100ul
Category	Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC, ICC, IHC-P
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Protein name	Endothelial PAS domain-containing protein 1
Molecular weight	96 kDa
Product format	Liquid
Gene id	2034
Reconstitution and storage	Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Description of target	Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
Purification	Antigen-specific affinity chromatography
Clonality	Polyclonal
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Immunogen	Range: Cys339 - Gln541
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/9/2025

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