PPM1A Antibody

Item no.	OACD06666
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Targets for Rodent Neurosciences Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Lymphoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Adenocarcinoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Autophagy Primary Antibodies By Organ Colorectal Cancer Neurodegeneration Markers Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PP2CA;PP2Calpha;PP2C-ALPHA;protein phosphatase 1A;Protein phosphatase 2C isoform alpha;Protein phosphatase IA.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	36 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	PPM1A
Gene Fullname	protein phosphatase, Mg2+/Mn2+ dependent 1A
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Nucleotide accession_num	NM_021003
Protein accession_num	NP_066283.1
Protein name	Protein phosphatase 1A
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Gly2 - Try382
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against PPM1A. It has been selected for its ability to recognize PPM1A in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 2/12/2026

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