« Back
Home /
CD126 Antibody

CD126 Antibody

Item no.	OADB00035
Manufacturer	AVIVA Systems Biology
Amount	200 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies Glial Cell Markers
Type	Antibody Monoclonal
Format	Lyophilized
Applications	FC, IP, IHC-F
Clone	B-R6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Burger R. et al., The Haematology Journal, 2001; 2: 42-53 Clement C. et al, CR.3.2 Leucocyte Typing V, Boston, 1993 Dubois B. et al., J. Immunol., 1999; 162 : 3428 -3436 Dubois B. et al., J. Immunol., 1998; 161 : 2223 -2231 Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97. Menetrier-Caux C. et al., Blood, 1998; 92 : 4778 - 4791 Muller-Newen, G. et al., Eur J Biochem.,1996; 236(3): 837-42
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	IL6Q,gp80,CD126,HIES5,IL-6R,IL6RA,IL6RQ,IL-1Ra,IL-6RA,IL6QTL,IL-6R-1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	52 kDa
Gene symbol	CD126
Gene Fullname	interleukin 6 receptor
Product format	Lyophilized
Reconstitution and storage	Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Nucleotide accession_num	NM_000565.3
Protein accession_num	NP_000556.1
Protein name	interleukin-6 receptor subunit alpha
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises the Interleukin-6 RÎ± subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
Biological activity	Blocks IL-6 induced proliferation of XG-1 cells, Inhibits IL-6 binding to its receptor, Recognises soluble and membrane bound IL-6 R
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OADB00035-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 200 ug

available

Delivery expected until 12/25/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer