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CD25 Antibody

CD25 Antibody

Item no.	OADB00124
Manufacturer	AVIVA Systems Biology
Amount	200 ug
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Applications	FC
Clone	B-B10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Charlot-Rabiega, P. et al., J. Biol. Chem.,2011; 286:27350-27362 Engert, A. et al., Int J Cancer,1991; 49(3): 450-6. Groux, H. et al., J Immunol.,1998; 160(7): 3188-93. Herbelin, C. et al., Bone Marrow Transplant,1994; 13(5): 563-9. Herve, P. et al., Blood,1990; 75(4): 1017-23. Herve, P. et al., Lancet,1988; 2(8619): 1072-3. Heyll, A. et al., Dtsch Med Wochenschr.,1991; 116(22): 852-6. Mousson, C. et al.,Transplant Proc.,1995; 27(2): 1727-8. Nakatani, T. et al., Protein Eng.1994; 7(3): 435-43. Nevill, T. J. et al.,Blood,1998; 92(6): 1910-7. Oppmann, B. et al., Immunity,2000; 13(5): 715-25. Ozsahin, H. et al., Blood,1998; 92(8): 2719-24. Racadot, E. et al., Bone Marrow Transplant,1995; 15(5): 669-77. Racadot, E. et al.,Transplant Proc.,1995; 27(2): 1672-3. Regeer, R. R. and D. Markovich, Am J Physiol Cell Physiol.,2004; 287(2): C365-72. Tazzari, P. L. et al.,Transplantation,1992; 54(2): 351-6. Tiberghien, P. et al.,Transplantation,1991; 52(3): 475-80. Wijdenes, J. et al., Dev Biol Stand.,1990; 71: 103-11. Zambello, R. et al., Blood,1997; 89(1): 201-11.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	p55,CD25,IL2R,IMD41,TCGFR,IDDM10
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	31 kDa
Gene symbol	CD25
Gene Fullname	interleukin 2 receptor subunit alpha
Product format	Lyophilized
Reconstitution and storage	Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Nucleotide accession_num	NM_000417.2
Protein accession_num	NP_000408.1
Protein name	interleukin-2 receptor subunit alpha
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises the Interleukin 2 Receptor Î± chain (IL-2 Ra), a 55 kDa protein
Biological activity	Inhibits Mixed Lymphocyte Culture, Recognises only membrane bound human IL-2 Ra
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

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Delivery expected until 12/25/2025

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