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IL-17A Antibody (OADB00329)

IL-17A Antibody (OADB00329)

Manufacturer	AVIVA Systems Biology
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines Primary Antibodies Neutralization
Type	Antibody Monoclonal
Specific against	other
Isotype	IgG2b
Applications	Neutralization
Amount	500 ug
Host	Mouse
Item no.	OADB00329
eClass 6.1	32160702
eClass 9.0	42030590
Available
Gene symbol	IL-17A
Protein name	interleukin-17A
Molecular weight	18 kDa
Product format	Lyophilized
Gene id	3605
Reconstitution and storage	Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Purification	Ion exchange chromatography
Biological activity	Neutralises the bioactivity of IL-17A on keratinocytes cell line HaCaT
Clonality	Monoclonal
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

available

Delivery expected until 5/30/2024