ETV1 Antibody (OAEC04453)

Wet Ice

Ascitic fluid containing 0.03% sodium azide

ETV1. ets variant gene 1. Several members of the Ets gene fam ily encode sequence-specific D NA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, tes tis, lung and heart. ER81 is also moderately expres sed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expres sion patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAP KAP kinase 2 inhibits ER81.

Purified recombinant fragment of ETV1 (aa1-191) expressed in EColi.