EPHB4 Antibody (OAEC04497)

108 kDa

2050

EphB4. EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein. NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand fam ily. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycos ylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyros ine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.

Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.