« Back
Home /
ITGAM Antibody

ITGAM Antibody

Item no.	OAEE00616
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg (C100)
Category	Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies Oligodendrocyte Markers
Type	Antibody Monoclonal
Applications	FC
Clone	M1/70
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rabbit (Oryctolagus cuniculus), Primate
Host	Rat
Isotype	IgG2b
Conjugate/Tag	APC
Citations	Takagi H, Numazaki M, Kajiwara T, Abe Y, Ishii M, Kato C, Kojima N: Cooperation of specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) and complement receptor type 3 (CR3) in the uptake of oligomannose-coated liposomes by macrophages. Glycobiology. 2009 Mar;19(3):258-66. Leon F, Contractor N, Fuss I, Marth T, Lahey E, Iwaki S, la Sala A, Hoffmann V, Strober W, Kelsall BL: Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis. J Immunol. 2006 Nov 15;177(10):6974-82. Brickson S, Ji LL, Schell K, Olabisi R, St Pierre Schneider B, Best TM: M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury. J Appl Physiol. 2003 Sep;95(3):969-76. Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC: Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002 Mar 15;168(6):3088-98. Welt FG, Edelman ER, Simon DI, Rogers C: Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries. Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2553-8. Dembic Z, Schenck K, Bogen B: Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2697-702. Whiteland JL, Nicholls SM, Shimeld C, Easty DL, Williams NA, Hill TJ: Immunohistochemical detection of T-cell subsets and other leukocytes inparaffin-embedded rat and mouse tissues with monoclonal antibodies. J Histochem Cytochem. 1995 Mar;43(3):313-20. Sanchez-Madrid F, Simon P, Thompson S, Springer TA: Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med. 1983 Aug 1;158(2):586-602. Ault KA, Springer TA: Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol. 1981 Jan;126(1):359-64. Springer T, Galfrè G, Secher DS, Milstein C: Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur J Immunol. 1978 Aug;8(8):539-51.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD11 antigen-like family member B;Cd11b;CD11B (p170);CD11b/CD18;cell surface glycoprotein MAC-1 alpha subunit;cell surface glycoprotein MAC-1 subunit alpha;complement receptor type 3;CR;CR3;CR-3 alpha chain;CR3A;F730045J24Rik;integrin alpha-M;leukocyte adhesion receptor MO1;Ly-4;Ly-40;Mac-;Mac-1;MAC1;Mac-1 alpha;Mac-1a;macrophage antigen alpha.
Shipping Condition	Cool pack
Available
Specificity	Human, Mouse, Non-human Primate, Rabbit
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	Itgam
Gene Fullname	integrin alpha M
Product format	Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Nucleotide accession_num	NM_000632.3; NM_001145808.1
Protein accession_num	NP_000623.2; NP_001139280.1
Protein name	Integrin alpha-M
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	B10 mouse spleen cells enriched for T cells
Manufacturer - Specificity	The rat monoclonal antibody M1/70 detects CD11b (integrin alphaM subunit), a type I transmembrane protein mainly expressed on monocytes/macrophages, granulocytes and NK-cells, which associates with CD18 to form Mac-1 integrin that plays important role in cell-cell interactions.
Formulation	APC
Concentration	0.5 mg/ml
Storage Buffer	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAEE00616-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg (C100)

available

Delivery expected until 1/8/2026

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer