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PDGFRB Antibody

PDGFRB Antibody

Item no.	OAEE00644
Manufacturer	AVIVA Systems Biology
Amount	100 tests (T100)
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Immunohistochemistry Western Blot ELISA Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	18A2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	APC
Citations	Fekete N, Rojewski MT, FÃ¼rst D, Kreja L, Ignatius A, Dausend J, Schrezenmeier H: GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS One. 2012;7(8):e43255. doi: 10.1371/journal.pone.0043255 Faraone D, Aguzzi MS, Toietta G, Facchiano AM, Facchiano F, Magenta A, Martelli F, Truffa S, Cesareo E, Ribatti D, Capogrossi MC, Facchiano A: Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. Neoplasia. 2009 Aug;11(8):732-42. Schmahl J, Rizzolo K, Soriano P: The PDGF signaling pathway controls multiple steroid-producing lineages. Genes Dev. 2008 Dec 1;22(23):3255-67. French WJ, Creemers EE, Tallquist MD: Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function. Mol Cell Biol. 2008 Sep;28(18):5646-57. Andrae J, Gallini R, Betsholtz C: Role of platelet-derived growth factors in physiology and medicine. Genes Dev. 2008 May 15;22(10):1276-312.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Activated tyrosine kinase PDGFRB;beta-type platelet-derived growth factor receptor;CD140 antigen-like family member B;CD140B;IBGC4;IMF1;JTK12;KOGS;NDEL1-PDGFRB;PDGFR;PDGFR1;PDGFR-1;PDGFR-beta;PDGF-R-beta;PENTT;platelet-derived growth factor receptor 1;platelet-derived growth factor receptor beta;platelet-derived growth factor receptor,beta polypeptide.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PDGFRB
Gene Fullname	platelet derived growth factor receptor beta
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Nucleotide accession_num	NM_002609.3
Protein accession_num	NP_002600.1
Protein name	receptor protein-tyrosine kinase
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	CD140b-transfected NIH 3T3 cells
Manufacturer - Specificity	The monoclonal antibody 18A2 recognizes CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
Formulation	APC
Concentration	10 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests (T100)

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Delivery expected until 1/8/2026

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