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CCR5 Antibody

CCR5 Antibody

Item no.	OAEE00700
Manufacturer	AVIVA Systems Biology
Amount	100 tests (T100)
Category	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Carcinoma Flow Cytometry Immunoprecipitation Western Blot ELISA Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	T21/8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	APC
Citations	Mascalchi P, Lamort AS, SalomÃ© L, Dumas F: Single Particle Tracking reveals two distinct environments for CD4 receptors at the surface of living T lymphocytes. Biochem Biophys Res Commun. 2012 Jan 6;417(1):409-13 Monde K, Maeda Y, Tanaka Y, Harada S, Yusa K: Gp120 V3-dependent impairment of R5 HIV-1 infectivity due to virion-incorporated CCR5. J Biol Chem. 2007 Dec 21;282(51):36923-32. HÃ¼ttenrauch F, Pollok-Kopp B, Oppermann M: G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers. J Biol Chem. 2005 Nov 11;280(45):37503-15. Pollok-Kopp B, Schwarze K, Baradari VK, Oppermann M: Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies. J Biol Chem. 2003 Jan 24;278(4):2190-8.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	C-C chemokine receptor type 5;C-C motif chemokine receptor 5 A159A;CCCKR5;CC-CKR-5;CCR-5;CD195;chemokine (C-C motif) receptor 5;chemokine receptor CCR5;chemokine recptor CCR5 Delta32;chemr13;CKR5;CKR-5;CMKBR5;HIV-1 fusion coreceptor;IDDM22;mutant C-C motif chemokine receptor.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CCR5
Gene Fullname	C-C motif chemokine receptor 5
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.
Nucleotide accession_num	NM_000579.3; NM_001100168.1
Protein accession_num	NP_000570.1; NP_001093638.1
Protein name	C-C chemokine receptor type 5
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	CCR5 peptide (Met1-Lys22) KLH conjugate
Manufacturer - Specificity	The mouse monoclonal antibody T21/8 recognizes the N-teminus of CD195, an approximately 45 kDa G-protein coupled receptor 1 family protein expressed on resting T cells, monocytes, macrophages, and immature dendritic cells.
Formulation	APC
Concentration	10 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests (T100)

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Delivery expected until 1/8/2026

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