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CR1 Antibody

CR1 Antibody

Item no.	OAEE00828
Manufacturer	AVIVA Systems Biology
Amount	100 tests (T100)
Category	Neuroscience Neuroinflammation Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	E11
Specific against	Human (Homo sapiens), Primate
Host	Mouse
Isotype	IgG1
Conjugate/Tag	FITC
Citations	Hogg N, Ross GD, Jones DB, Slusarenko M, Walport MJ, Lachmann PJ: Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). Eur J Immunol. 1984 Mar;14(3):236-43. Leukocyte Typing III., McMichael M.J. et al. (Eds.), Oxford University Press (1987); p.611. Nielsen CH, Pedersen ML, Marquart HV, Prodinger WM, Leslie RG: The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells. Eur J Immunol. 2002 May;32(5):1359-67. Kremlitzka M, PolgÃ¡r A, FÃ¼lÃ¶p L, Kiss E, PoÃ³r G, Erdei A: Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients. Int Immunol. 2012 Sep 7. [Epub ahead of print]
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	C3b/C4b receptor;C3-binding protein;C3BR;C4BR;CD35;CD35 antigen;complement component (3b/4b) receptor 1 (Knops blood group);complement receptor 1;complement receptor type 1;KN;Knops blood group antigen.
Shipping Condition	Cool pack
Available
Specificity	Human, Non-human Primate
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CR1
Gene Fullname	complement C3b/C4b receptor 1 (Knops blood group)
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	Mediates cellular binding of particles and immune complexes that have activated complement.
Nucleotide accession_num	NM_000573.3; NM_000651.4
Protein accession_num	NP_000564.2; NP_000642.3
Protein name	Complement receptor type 1
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Acute monocytic leukemia cells and normal blood monocytes
Manufacturer - Specificity	The mouse monoclonal antibody E11 recognizes CD35 (CR1), a type I glycoprotein expressed on granulocytes, monocytes, B cells, folicular dendritic cells, erythrocytes, NK and T cell subsets, as well as e.g. on glomerulal podocytes.
Formulation	FITC
Concentration	4 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests (T100)

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Delivery expected until 1/8/2026

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