CD55 Antibody

Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies

CD55

Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829).

NP_000565.1; NP_001108224.1; NP_001287832.1; NP_001287833.1

Monoclonal

HPB-ALL human T cell line

FITC

The reagent is provided in Tris buffered saline (TBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.