DPYSL2 Antibody

Polyclonal Antibody

Wet Ice

DPYSL2

Liquid

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer' s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NP_001184222.1

Polyclonal

Recombinant protein encompassing a sequence within the N-terminus region of human CRMP2. The exact sequence is proprietary.

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.