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IL10 Antibody

IL10 Antibody

Item no.	OAGA08591
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies Neuronal Cell Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	GT5111
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CSIF,TGIF,GVHDS,IL-10,IL10A
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	WB, IHC-FFPE
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	21 kDa
Manufacturer - Application Additional Information	IHC-FFPE: 1:100~1000 WB: 1:1000~10000
Gene symbol	IL10
Gene Fullname	interleukin 10
Product format	Liquid PBS
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Nucleotide accession_num	NM_000572.2
Protein accession_num	NP_000563.1
Protein name	interleukin-10
Clonality	Monoclonal
Purification	Affinity purified by Protein G.
Immunogen	Recombinant protein encompassing a sequence within the center region of human IL10. The exact sequence is proprietary.
Homology	Cat (86%), Rabbit (83%), Sheep (85%), Rhesus Monkey (93%), Chimpanzee (98%), Bovine (81%), Guinea Pig (88%)
Concentration	1.19 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAGA08591-datasheet.pdf

OAGA08591-safety-datasheet.pdf