« Back
Home /
NOX2 Antibody - N-terminal (OAPB01933)

NOX2 Antibody - N-terminal (OAPB01933)

Manufacturer	AVIVA Systems Biology
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	IgG
Applications	WB, IF, IHC-P
Amount	100 ug
Host	Rabbit
Item no.	OAPB01933
eClass 6.1	32160702
eClass 9.0	32160702
Available
Gene symbol	CYBB
Protein name	cytochrome b-245 heavy chain
Product format	Liquid, 1 mg/mL provided in PBS containing 0.02% sodium azide.
Gene id	1536
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX2, also known as cytochrome b beta (CYBB) is one of two proteins that make up Cytochrome b-245, thought to be a primary component of the microbicidal oxidase system of phagocytes. NOX2 deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) (2). Activation of the NOX2 enzyme complex in microglia is thought to be neurotoxic and may play a role in Alzheimera€s and Parkinsona€s disease (3).
Purification	Affinity chromatography purified via peptide column
Clonality	Polyclonal
Immunogen	Rabbit polyclonal NOX2 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX2.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 6/13/2024