TAU Antibody - N-terminal

Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot

Wet Ice

MAPT

Liquid. TAU antibody is supplied in PBS containing 0.02% sodium azide.

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

https://www.ncbi.nlm.nih.gov/protein/NP_058519

Polyclonal

TAU antibody was raised against a 19 amino acid peptide near the amino terminus of human TAU. The immunogen is located within amino acids 210 - 260 of TAU.