Comparison

Rabbit antibody to Optineurin

Item no. OSO00040W
Manufacturer Osenses
Amount 100ul
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias OPTN, Optic neuropathy-inducing protein, E3-14.7K-interacting protein<br/>FIP-2, Huntingtin-interacting protein L, Huntingtin yeast partner L, Huntingtin-interacting protein 7, HIP-7, NEMO-related protein, Transcription factor IIIA-interacting protein, TF
Similar products OPTN, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, HIP-7, TFIIIA-IntP, Transcription factor IIIA-interacting protein, E3-14.7K-interacting protein
FIP-2
Available
Also known
OPTN, Optic neuropathy-inducing protein, E3-14.7K-interacting protein
FIP-2, Huntingtin-interacting protein L, Huntingtin yeast partner L, Huntingtin-interacting protein 7, HIP-7, NEMO-related protein, Transcription factor IIIA-interacting protein, TFIIIA-IntP
Target
FUNCTION: Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD).
SUBCELLULAR LOCATION: Cytoplasm a€C perinuclear region. Golgi apparatus. Note: Found in the perinuclear region and associates with the Golgi apparatus.
TISSUE SPECIFICITY: In eye, it is expressed in anterior segment, retina, and optic nerve blood vessels (at protein level). Highly expressed in adult liver, heart and testis.
Spcs X-react.
Mouse. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1 : 2000 is recommended for WB and 1 : 1000 IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Rezaie T, et al. Genomics 85:131-138(2005)
Limitation
For research use only
Immunogen
A synthetic peptide from internal region of mouse Optineurin conjugated to blue carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/Q8K3K8
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for Optineurin.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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