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Rabbit antibody to Optineurin

Rabbit antibody to Optineurin

Item no.	OSO00040W
Manufacturer	Osenses
Amount	100ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	OPTN, Optic neuropathy-inducing protein, E3-14.7K-interacting protein<br/>FIP-2, Huntingtin-interacting protein L, Huntingtin yeast partner L, Huntingtin-interacting protein 7, HIP-7, NEMO-related protein, Transcription factor IIIA-interacting protein, TF
Similar products	OPTN, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, HIP-7, TFIIIA-IntP, Transcription factor IIIA-interacting protein, E3-14.7K-interacting protein FIP-2
Available
Also known	OPTN, Optic neuropathy-inducing protein, E3-14.7K-interacting protein FIP-2, Huntingtin-interacting protein L, Huntingtin yeast partner L, Huntingtin-interacting protein 7, HIP-7, NEMO-related protein, Transcription factor IIIA-interacting protein, TFIIIA-IntP
Target	FUNCTION: Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD). SUBCELLULAR LOCATION: Cytoplasm a€C perinuclear region. Golgi apparatus. Note: Found in the perinuclear region and associates with the Golgi apparatus. TISSUE SPECIFICITY: In eye, it is expressed in anterior segment, retina, and optic nerve blood vessels (at protein level). Highly expressed in adult liver, heart and testis.
Spcs X-react.	Mouse. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1 : 2000 is recommended for WB and 1 : 1000 IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Rezaie T, et al. Genomics 85:131-138(2005)
Limitation	For research use only
Immunogen	A synthetic peptide from internal region of mouse Optineurin conjugated to blue carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/Q8K3K8
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for Optineurin.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 10/16/2025

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