Rabbit antibody to VAMP3

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
FUNCTION: Trafficking protein from a constitutively recycling pathway.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.

IHC, WB. A working concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

12 months after reconstitution

1. Bernstein A.M, et al. Blood 93:571-579(1999).

A synthetic peptide from mouse VAMP3 conjugated to blue carrier protein was used as the antigen.

http://kr.expasy.org/uniprot/Q15836
http://kr.expasy.org/uniprot/P63025
http://kr.expasy.org/uniprot/P63024

Polyclonal

Lyophilised