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COMP Antibody

COMP Antibody

Manufacturer	ProSci
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse
Format	Liquid
Applications	WB, IHC
Amount	50 uL
Host	Rabbit
Item no.	PRS-16-556-50uL
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction, Stem Cell
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_000086.2).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	COMP
Ncbi Gene Id #	1311
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	COMP
Ncbi Official Full Name	cartilage oligomeric matrix protein
Ncbi Organism	Homo sapiens
Swissprot #	P49747
Background	The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
1st Image Caption	Immunohistochemistry of paraffin-embedded mouse liver using COMP antibody (16-556) at dilution of 1:100 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 6/6/2024