BCMA Antibody

Blue Ice

Predicted: 20 kD

Observed: 22 kD

BCMA Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-κ B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Trial Size

23238192

PRS-1306-0.1mg

PRS-1306-0.1mg

1 mg/mL

WB: 1-4 μ g/mL; IHC-P: 1-5 μ g/mL; IHC-P/IF: 10-20 μ g/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.