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Comparison

ARTS Antibody

Item no. PRS-3025-0.02mg
Manufacturer ProSci
Amount 0.02 mg
Quantity options 0.02 mg 0.1 mg
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, ELISA, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Larisch S, Yi Y, Lotan R, Kerner H, et al. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nat Cell Biol 2000;2(12):915-21
Depraetere V. The ARTS of apoptosis. Nat Cell Biol. 2000;2(12):E219.
Paavola,P., Horelli-Kuitunen,N., Palotie,A. and Peltonen,L. Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. Genomics 1999;55 (1):122-125
Zieger,B., Tran,H., Hainmann, I. , Wunderle,D., Zgaga-Griesz,A., Blaser,S. and Ware,J. Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. Gene 2000;261(2):197-203
NCBI Sep 04
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ARTS Antibody: H5,ARTS,MART,SEP4,CE5B3,PNUTL2,hucep-7,BRADEION,hCDCREL-2,Septin-4,Apoptosis-related protein in the TGF-beta signaling pathway
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
ARTS antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
32 kDa
Manufacturer - Research Area
Apoptosis
Background
ARTS Antibody: Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-α and Fas ligand.
By Type
Apoptosis
Badges
Trial Size
Modifications
None
Protein Gi #
12024871
Purification
ARTS Antibody is affinity chromatography purified via peptide column.
Positive Control 1
PRS-1302-0.1mg
Positive Control 2
PRS-1306-0.1mg
Positive Control 3
PRS-1305-0.1mg
Positive Control 4
PRS-10-101-4um
Concentration
1 mg/mL
Buffer
ARTS Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
ARTS antibody can be used for detection of ARTS by Western blot at 2 μ g/mL. A band at 32 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 2 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Immunogen
ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.

The immunogen is located within the first 50 amino acids of ARTS.
Clonality
Polyclonal
NCBI Official Name
septin 4
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.02 mg
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