BAFF Receptor Antibody

Blue Ice

20 kDa

BAFF Receptor Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-κ B and c-jun N-terminal kinase.

Trial Size

15208475

PRS-1306-0.1mg

PRS-1466-0.1mg

PRS-10-901-4um

BAFF Receptor Antibody is supplied in PBS containing 0.02% sodium azide.

BAFF Receptor antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin.

The immunogen is located within the last 50 amino acids of BAFF Receptor.

tumor necrosis factor receptor superfamily, member 13C

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.