TLR8 Antibody

TLR8 antibody can be used for detection of TLR8 by immunohistochemistry at 5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.

Antibody validated: Immunohistochemistry in human and mouse samples. All other applications and species not yet tested.

TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

TLR8 Antibody is affinity chromatography purified via peptide column.

TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.

Polyclonal

Homo sapiens