T-cadherin Antibody

Primary Antibodies

Blue Ice

Predicted: 78, 84 kDa
Observed: 85 kDa

T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Trial Size

1705552

PRS-1212-0.1mg

PRS-17-004-1pack

1 mg/mL

T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μ g/mL. Antibody can also be used for for immunohistochemistry starting at 5 μ g/mL and immunocytochemistry starting at 20 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

At least two isoforms of T-cadherin are known to exist.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.