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IL-2 Antibody

IL-2 Antibody

Item no.	PRS-38-204-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, ELISA, NT
Specific against	Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
NCBI	Il2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Il-2,Interleukin-2,T-cell growth factor,IL-2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies, Functional Antibodies, Antibody Pairs
Manufacturer - Applications	ELISA, WB, Neutralization Assay
Shipping Temperature	Room Temp
Storage Conditions	IL-2 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Manufacturer - Research Area	Immunology, Chemokines & Cytokines, Antibody Pairs, Functional Assays
Background	Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
By Type	Immunology, Chemokines & Cytokines
Modifications	None
Protein Gi #	124328
Concentration	batch dependent
Application Note	Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Rat IL-2 (1.0 ng/mL), a concentration of < 0.1 μ g/mL of this antibody is required. ELISA: Indirect: To detect Rat IL-2 by indirect ELISA (using 100 μ L/well antibody solution) a concentration of 0.5 - 2.0 μ g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL-2. Sandwich To detect Rat IL-2 by sandwich ELISA (using 100 μ L/well antibody solution) a concentration of 0.5 - 2.0 μ g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Rat IL-2 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL-2. Western Blot: To detect Rat IL-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant Rat IL-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Immunogen	Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Rat IL-2. Rat IL-2 specific antibody was purified by affinity chromatography employing immobilized Rat IL-2 matrix.
Clonality	Polyclonal
NCBI Official Name	interleukin 2
NCBI Organism	Rattus norvegicustus norvegicus
Disclaimer	This product is for research use only.
User Note	Centrifuge vial prior to opening.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/6/2025

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