RP105 Antibody

Primary Antibodies

+4C storage

RP105 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Trial Size

1843411

PRS-1306-0.1mg

1 mg/mL

RP105 antibody can be used for the detection of RP105 by Western blot at 0.5 - 1 μ g/mL. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa. Antibody can also be used for immunohistochemistry starting at 2 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

RP105 antibody was raised against a 11 amino acid synthetic peptide from near the amino terminus of human RP105.

The immunogen is located within the first 50 amino acids of RP105.

CD180 molecule

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.