MD-1 Antibody

Primary Antibodies

MD-1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

MD-1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Trial Size

4758708

PRS-1224-0.1mg

PRS-10-901-4um

MD-1 Antibody is supplied in PBS containing 0.02% sodium azide.

MD-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MD-1.

The immunogen is located within the last 50 amino acids of MD-1.

lymphocyte antigen 86

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.