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STIM-1 Antibody

STIM-1 Antibody

Manufacturer	ProSci
Category	Oncology Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Specific against	Human
Format	Liquid
Applications	WB, IHC, ELISA
Amount	0.1 mg
Host	Rabbit
Item no.	PRS-39-873-0.1mg
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	Dry Ice
By Research Area	Immunology, Cancer
Immunogen	A synthetic peptide corresponding to a region near the N-terminus.
Applications	ELISA, Western (immuno) blotting, Immunostaining (in testing)
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Disclaimer	This product is for research use only.
Modifications	None
Ncbi Official Symbol	STIM1
Accession #	EAX02580
Protein Gi #	209572721
Ncbi Gene Id #	6786
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	APP
Ncbi Official Full Name	stromal interaction molecule 1
Ncbi Organism	Homo sapiens
Swissprot #	Q13586
Background	STIM-1 is a component of the Ca sensor/channel. It associates with ORAI-1 and form a essential complex involved in store-operated channels. STIM1 activates Ca(2+) influx via Orai1 channels. Expression of STIM and Orai proteins are found in many cell types and knock-out mice lack viability.
Background References 1	Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA., Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation., Biochim Biophys Acta. 2002 Apr 1; 1596(1):131-137
Background References 2	Dziadek MA, Johnstone LS., Biochemical properties and cellular localisation of STIM proteins., Cell Calcium. 2007 Aug; 42(2):123-32.
Background References 3	Frischauf I, Schindl R, Derler I, Bergsmann J, Fahrner M, Romanin C., .The STIM/Orai coupling machinery., Channels (Austin). 2008 Jul-Aug; 2(4):261-8

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 6/6/2024