CLDN6 Antibody

For WB starting dilution is: 1:1000

blue ice or room temperature

23 kDa

Tight junctions represent one mode of cell-to-celladhesion in epithelial or endothelial cell sheets, formingcontinuous seals around cells and serving as a physical barrier toprevent solutes and water from passing freely through theparacellular space. These junctions are comprised of sets ofcontinuous networking strands in the outwardly facing cytoplasmicleaflet, with complementary grooves in the inwardly facingextracytoplasmic leaflet. This gene encodes a component of tightjunction strands, which is a member of the claudin family. Theprotein is an integral membrane protein and is one of the entrycofactors for hepatitis C virus. The gene methylation may beinvolved in esophageal tumorigenesis. This gene is adjacent toanother family member CLDN9 on chromosome 16.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This CLDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human CLDN6.

Claudin-6

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.