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COPE Antibody

COPE Antibody

Manufacturer	ProSci
Category	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Macrophage Markers
Type	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applications	WB, IF, IHC-P
Amount	400 ul
Host	Rabbit
Item no.	PRS-55-787-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Chicken, Hamster, Mouse
Immunogen	This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Predicted Molecular Weight	34 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	COPE
Accession #	O14579
Ncbi Gene Id #	11316
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	COPE
Ncbi Official Full Name	Coatomer subunit epsilon
Ncbi Organism	Homo sapiens
Swissprot #	O14579
Background	The product of this gene is an epsilon subunit of coatomerprotein complex. Coatomer is a cytosolic protein complex that bindsto dilysine motifs and reversibly associates with Golginon-clathrin-coated vesicles. It is required for budding from Golgimembranes, and is essential for the retrograde Golgi-to-ERtransport of dilysine-tagged proteins. Coatomer complex consists ofat least the alpha, beta, beta', gamma, delta, epsilon and zetasubunits. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Background References 1	Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background References 2	Morikawa, R.K., et al. J. Biol. Chem. 284(39):26620-26630(2009)
Background References 3	Maruyama, S., et al. Mol. Cell. Biochem. 307 (1-2), 73-82 (2008) :
Background References 4	Goryachev, A.B., et al. PLoS Comput. Biol.(12), E172 (2006) :
1st Image Caption	Western Blot at 1:1000 dilution Lane 1: A375 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.
2nd Image Caption	COPE Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3rd Image Caption	Confocal immunofluorescent analysis of COPE Antibody with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 6/6/2024