GRIA4 Antibody

Primary Antibodies

Blue Ice

101 kDa

Glutamate receptors are the predominant excitatory
neurotransmitter receptors in the mammalian brain and are activated
in a variety of normal neurophysiologic processes. These receptors
are heteromeric protein complexes composed of multiple subunits,
arranged to form ligand-gated ion channels. The classification of
glutamate receptors is based on their activation by different
pharmacologic agonists. The subunit encoded by this gene belongs to
a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole
propionate)-sensitive glutamate receptors, and is subject to RNA
editing (AGA->GGA; R->G). Alternative splicing of this gene results
in transcript variants encoding different isoforms, which may vary
in their signal transduction properties. Some haplotypes of this
gene show a positive association with schizophrenia. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Rat, Pr

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.