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RORC Antibody

RORC Antibody

Manufacturer	ProSci
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	PRS-57-272-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Cancer, Cell Cycle, Neuroscience, Signal Transduction
Immunogen	This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	58 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	RORC
Accession #	P51449
Protein Gi #	49066040
Ncbi Gene Id #	6097
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	RORC
Ncbi Official Full Name	Nuclear receptor ROR-gamma
Ncbi Organism	Homo sapiens
Swissprot #	P51449
Background	The protein encoded by this gene is a DNA-bindingtranscription factor and is a member of the NR1 subfamily ofnuclear hormone receptors. The specific functions of this proteinare not known; however, studies of a similar gene in mice haveshown that this gene may be essential for lymphoid organogenesisand may play an important regulatory role in thymopoiesis. Inaddition, studies in mice suggest that the protein encoded by thisgene may inhibit the expression of Fas ligand and IL2. Twotranscript variants encoding different isoforms have been found forthis gene.
Background References 1	Wang, Y., et al. Biochim. Biophys. Acta 1801(8):917-923(2010)
Background References 2	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background References 3	Burgler, S., et al. J. Immunol. 184(11):6161-6169(2010)
Background References 4	Jin, L., et al. Mol. Endocrinol. 24(5):923-929(2010)
1st Image Caption	Western blot analysis in CEM cell line lysates (35ug/lane).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 6/6/2024