RPS19 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Ribosomes, the organelles that catalyze protein synthesis,
consist of a small 40S subunit and a large 60S subunit. Together
these subunits are composed of 4 RNA species and approximately 80
structurally distinct proteins. This gene encodes a ribosomal
protein that is a component of the 40S subunit. The protein belongs
to the S19E family of ribosomal proteins. It is located in the
cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia
(DBA), a constitutional erythroblastopenia characterized by absent
or decreased erythroid precursors, in a subset of patients. This
suggests a possible extra-ribosomal function for this gene in
erythropoietic differentiation and proliferation, in addition to
its ribosomal function. Higher expression levels of this gene in
some primary colon carcinomas compared to matched normal colon
tissues has been observed. As is typical for genes encoding
ribosomal proteins, there are multiple processed pseudogenes of
this gene dispersed through the genome.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.