NR3C2 Antibody

For WB starting dilution is: 1:1000

blue ice or room temperature

107 kDa

This gene encodes the mineralocorticoid receptor, whichmediates aldosterone actions on salt and water balance withinrestricted target cells. The protein functions as aligand-dependent transcription factor that binds tomineralocorticoid response elements in order to transactivatetarget genes. Mutations in this gene cause autosomal dominantpseudohypoaldosteronism type I, a disorder characterized by urinarysalt wasting. Defects in this gene are also associated with earlyonset hypertension with severe exacerbation in pregnancy.Alternative splicing results in multiple transcript variants.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This NR3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human NR3C2.

Mineralocorticoid receptor

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.