ZNF346 Antibody

ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 μg/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

ZNF346 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ZNF346 Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.

ZNF346 Antibody is affinity chromatography purified via peptide column.

1 mg/ml

ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human ZNF346.

The immunogen is located within amino acids 70 - 120 of ZNF346.

zinc finger protein 346

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.