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IGF1R Antibody

IGF1R Antibody

Item no.	PRS-63-098-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neural Lineage Markers Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Song, R.X., et al., Proc. Natl. Acad. Sci. U.S.A. 101(7):2076-2081 (2004). Zhao, H., et al., Oncogene 23(3):786-794 (2004). Lu, Y., et al., Biochem. Biophys. Res. Commun. 313(3):709-715 (2004). Hakam, A., et al., Dig. Dis. Sci. 48(10):1972-1978 (2003).
NCBI	IGF1R
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Insulin-like growth factor 1 receptor,Insulin-like growth factor I receptor,IGF-I receptor,CD221,Insulin-like growth factor 1 receptor alpha chain,Insulin-like growth factor 1 receptor beta chain,IGF1R
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	155 kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Neuroscience, Signal Transduction
Background	The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
By Type	Cancer, Cell Cycle, Neuroscience, Signal Transduction
Modifications	None
Protein Gi #	124240
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen	This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.
Clonality	Polyclonal
NCBI Official Name	Insulin-like growth factor 1 receptor
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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