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ILK Antibody

ILK Antibody

Manufacturer	ProSci
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies Astrocytoma By Organ Bladder Cancer Colorectal Cancer Thyroid Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applications	WB, IHC-P
Amount	400 ul
Host	Rabbit
Item no.	PRS-63-101-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen	This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from human ILK.
Applications	For IHC-P starting dilution is: 1:50~100 For WB starting dilution is: 1:1000
Predicted Molecular Weight	51 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ILK
Accession #	Q13418
Protein Gi #	9973397
Ncbi Gene Id #	3611
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ILK
Ncbi Official Full Name	Integrin-linked protein kinase
Ncbi Organism	Homo sapiens
Swissprot #	Q13418
Background	Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Background References 1	Li, Y., et al., J. Clin. Invest. 112(4):503-516 (2003).
Background References 2	Troussard, A.A., et al., J. Biol. Chem. 278(25):22374-22378 (2003).
Background References 3	Marotta, A., et al., Br. J. Cancer 88(11):1755-1762 (2003).
Background References 4	Cordes, N., et al., Br. J. Cancer 88(9):1470-1479 (2003).
1st Image Caption	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ILK Antibody (S246) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
2nd Image Caption	Western blot analysis of anti-ILK Antibody (S246) in Hela cell line lysates (35ug/lane)
3rd Image Caption	Western blot analysis of ILK using rabbit polyclonal ILK Antibody (pS246) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ILK gene.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 7/4/2024