« Back
Home /
Paralemmin3 Antibody

Paralemmin3 Antibody

Item no.	PRS-6449-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Quantity options	0.02 mg 0.1 mg
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Antibodies Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Chen X, Wu X, Zhao Y, et al. A novel binding protein of single immunoglobulin IL-1 receptor-related molecule: Paralemmin-3. Biochem. Biophys. Res. Commun. 2011; 404:1029-33 Wald D, Qin J, Zhao Z, et al. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 2003; 4:920-7.
NCBI	PALM3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Paralemmin3 Antibody: Paralemmin-3
Available
Manufacturer - Applications	Paralemmin3 antibody can be used for detection of Paralemmin3 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	Paralemmin3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area	Innate Immunity
Background	Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.
Protein Gi #	222537747
Purification	Paralemmin3 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1219-0.1mg
Positive Control 2	PRS-17-012-1pack
Concentration	1 mg/ml
Buffer	Paralemmin3 Antibody is supplied in PBS containing 0.02% sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Mouse: (79%)
Immunogen	Paralemmin3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Paralemmin3. The immunogen is located within amino acids 50 - 100 of Paralemmin3.
Clonality	Polyclonal
NCBI Official Name	paralemmin 3
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 22 days

Compare

Add to wishlist

Get an offer