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ECRG1 Antibody

ECRG1 Antibody

Item no.	PRS-6521-0.02mg
Manufacturer	ProSci
Amount	0.02 mg
Quantity options	0.02 mg 0.1 mg
Category	Oncology Antibodies Western Blot ELISA Primary Antibodies By Organ Lung Cancer Colorectal Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Chicken
Isotype	IgY
Conjugate/Tag	Unconjugated
Citations	Yueying W, Jianbo W, Hailin L, et al. ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its inhibition effect on tumors. Carcinogenesis 2008; 29:157-60. Zhao N, Wang J, Cui Y, et al. Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1. J. Cell Biochem. 2004; 92:65-76 Zhao N, Huang G, Guo L, et al. ECRG1, a novel candidate of tumor suppressor gene in the esophageal carcinoma, triggers a senescent program in NIH3T3 cells. Exp. Biol. Med. 2006; 231:84-90.
NCBI	TMPRSS11A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ECRG1 Antibody: ECRG1,ECRG1,HATL1,HESP,Transmembrane protease serine 11A,Airway trypsin-like protease 1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	ECRG1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area	Cancer, Cell Cycle
Background	ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
By Type	Cancer, Cell Cycle
Badges	Trial Size
Modifications	None
Protein Gi #	167466250
Purification	ECRG1 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1404-0.1mg
Concentration	1 mg/mL
Buffer	ECRG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 μ g/mL. Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Manufacturer - Specificity	At least two isoforms of ECRG1 are known to exist; ECRG1 antibody is predicted to not cross-react with other ECRG family members.
Immunogen	ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1. The immunogen is located within amino acids 300 - 350 of ECRG1.
Clonality	Polyclonal
NCBI Official Name	transmembrane protease, serine 11A
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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