Comparison

NKX2-4 Antibody

Item no. PRS-6747-0.02mg
Manufacturer ProSci
Amount 0.02 mg
Quantity options 0.02 mg 0.1 mg
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Wang CC, Brodnicki T, Copeland NG, et al. Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm. Genome 2000; 11:466-8.
Small EM, Vokes SA, Garriock RJ, et al. Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes. Mech. Dev. 2000; 96:259-62.
Hill JT, Chao CS, Anderson KR, et al. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol. Endocrinol. 2010; 381-90.
NCBI NKX2-4
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NKX2-4 Antibody: NKX2D,NKX2.4,NKX2D,Homeobox protein NK-2 homolog D
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
NKX2-4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Stem Cell
Background
NKX2-4 Antibody: NKX2-4 (NK2 homeobox 4) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-4 is closely related to NKX2-1 and NKX2-4 and is specifically localized to the ventral diencephalon. Recent experiments in Xenopus have suggested that the homeodomain protein XANF is necessary for the activation of NKX2-4, but does not directly regulate its expression.
By Type
Stem Cell
Badges
Trial Size
Modifications
None
Protein Gi #
157426823
Purification
NKX2-4 Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Positive Control 2
Concentration
1 mg/mL
Buffer
NKX2-4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
NKX2-4 antibody can be used for detection of NKX2-4 by Western blot at 1 μ g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Homology
Predicted species reactivity based on immunogen sequence: Guinea pig: (100%), Rat: (86%), Chicken: (86%), Bovine: (71%)
Manufacturer - Specificity
NKX2-4 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-4 are known to exist; this antibody will detect both isoforms.
Immunogen
NKX2-4 antibody was raised against an 18 amino acid synthetic peptide near the center of human NKX2-4.

The immunogen is located within amino acids 220 - 270 of NKX2-4.
Clonality
Polyclonal
NCBI Official Name
NK2 homeobox 4
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.02 mg
Available: In stock
available

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